When approximately 90% of adults worldwide carry at least one type of herpes virus (such as HSV, EBV, and CMV), tools for the accurate detection and research of these "latent pathogens" become the core competitiveness in virology research. As a brand under the LGC Group focusing on virology reagents, Virusys has established itself as a reliable partner for researchers unraveling the mysteries of herpes viruses, backed by its strong capabilities—offering over 70 highly specific monoclonal antibodies and having one-third of its products featured in academic journals.

Herpes viruses are a group of enveloped double-stranded DNA viruses belonging to the Herpesviridae family. To date, more than 100 types of herpes viruses have been identified. Herpes viruses associated with human infections are referred to as Human Herpesviruses (HHV). Based on their genetic structure, homology, and related characteristics, human herpes viruses are classified into three subfamilies: Alphaherpesvirinae, Betaherpesvirinae, and Gammaherpesvirinae. Among them, HSV-1, HSV-2, and VZV belong to the Alphaherpesvirinae subfamily; HCMV, HHV-6, and HHV-7 belong to the Betaherpesvirinae subfamily; and EBV and HHV-8 belong to the Gammaherpesvirinae subfamily. These viruses can cause a variety of diseases, ranging from common oral and genital herpes to severe congenital infections and certain types of cancer. Understanding these viruses is conducive to better research on their biological characteristics, pathogenic mechanisms, and the development of corresponding therapeutic methods.

 

Herpes Virus Subfamily	Official Naming	Common Name	Target Cell	Tissue Tropism
Alpha(α)	Human Herpesvirus Type 1 (HHV-1)	Herpes Simplex Virus Type 1 (HSV-1)	Mucosal Epithelial Cells	Ganglion
	Human Herpesvirus Type 2 (HHV-2)	Herpes Simplex Virus Type 2 (HSV-2)	Mucosal Epithelial Cells	Ganglion
	Human Herpesvirus Type 3 (HHV-3)	Varicella-Zoster Virus (VZV)	Mucosal Epithelial Cells / T Cells	Ganglion
Beta(β）	Human Herpesvirus Type 5 (HHV-5)	Human Cytomegalovirus (HCMV)	Macrophages / Monocytes / Epithelial Cells	White Blood Cells / Epithelial Cells
	Human Herpesvirus Type 6 (HHV-6)	Human Herpesvirus Type 6（HHV-6）	T Lymphocytes / Monocytes / Macrophages	T Lymphocytes
	Human Herpesvirus Type 7(HHV-7)	Human Herpesvirus Type 7（HHV-7）	T Lymphocytes / Epithelial Cells / Fibroblasts	T Lymphocytes
Gamma(γ)	Human Herpesvirus Type 4 (HHV-4)	EB virus（EBV）	B Lymphocytes / Mucosal Epithelial Cells	B Lymphocytes (abbreviation: B Cells)
	Human Herpesvirus Type 8 (HHV-8)	Kaposi's Sarcoma-Associated Herpesvirus (KSHV)	Lymphocyte (plural: Lymphocytes)	Lymphocyte (plural: Lymphocytes)

1. Herpes Simplex Virus (HSV)

Herpes Simplex Virus (HSV) is a major pathogen that widely infects humans, mainly classified into two types: HSV-1 and HSV-2. Its infection can cause a variety of diseases, ranging from oral herpes to severe encephalitis. An in-depth understanding of the HSV life cycle is the foundation for developing effective diagnostic methods and intervention strategies.

HSV infection relies on a series of key proteins, among which envelope glycoproteins (such as gD, gB, gC, gE, gG, and gH/gL) are core targets. Specifically, gD is responsible for initiating binding to host receptors and serves as the primary target of neutralizing antibodies; while gB, due to its high conservation, has become a preferred target for the development of vaccines and therapeutic antibodies. Immediate-early proteins (such as ICP0 and ICP4) act as "switches" for viral gene expression—their presence marks the onset of viral infection and represents important potential targets for antiviral drug screening.

Targeting these core molecules, Virusys offers a range of validated, high-quality HSV antibodies. Whether for glycoprotein research aimed at uncovering viral entry mechanisms, or for the detection of immediate-early proteins during the early stage of viral replication, our products provide accurate recognition, flexible application, and reliable data support. We are committed to accelerating your research in the fields of vaccine development, diagnostic tool creation, and pathogenic mechanism exploration.

 

Item Number	English Name	Specification
VS-HA056-1	HSV gB Monoclonal Antibody	1  mg
VS-P1122	HSV gB Monoclonal Antibody (H126)	500  μg
VS-P1123	HSV gB Monoclonal Antibody (H1379)	500  μg
VS-P1105	HSV gB Monoclonal Antibody (H1817)	500  μg
VS-P1130	HSV gB-1 Monoclonal Antibody (H1435)	500  μg
VS-P1132	HSV gB-1 Monoclonal Antibody (H1815)	500  μg
VS-P1133	HSV gB-1 Monoclonal Antibody (H233)	500  μg
VS-P1104	HSV gC-1 Monoclonal Antibody (H633)	500  μg
VS-HA025-100	HSV gD Monoclonal Antibody	100  μg
VS-P1103	HSV gD Monoclonal Antibody (H170) 500μg	500  μg
VS-P1108	HSV gE-1 Monoclonal Antibody (H600)	500  μg
VS-P1109	HSV gE-2 Monoclonal Antibody (H222)	500  μg
VS-P1107	HSV gG-1 Monoclonal Antibody (H1379)	500  μg
VS-P1106	HSV gG-2 Purified Monoclonal Antibody	500  μg
VS-P1119	HSV ICP27 Monoclonal Antibody (H1142)	500  μg
VS-P1113	HSV ICP27 Monoclonal Antibody (H1113)	500  μg
VS-P1101	HSV ICP4  Monoclonal Antibody (H943)	500  μg
VS-P1120	HSV ICP6 Monoclonal Antibody (H121)	500  μg
VS-P1115	HSV ICP8 Monoclonal Antibody (H793)	500  μg
VS-H1A022-100	HSV-1 gC Monoclonal Antibody	100  μg
VS-H1A054-100	HSV-1 gE Monoclonal Antibody	100  μg
VS-H1A020-100	HSV-1 gG Monoclonal Antibody	100  μg
VS-H1A258-100	HSV-1 gH Monoclonal Antibody	100  μg
VS-H1A259-100	HSV-1 gL Monoclonal Antibody	100  μg
VS-H1A027-100	HSV-1 ICP0 Monoclonal Antibody	100  μg
VS-H1A021-100	HSV-1 ICP4 Monoclonal Antibody	100  μg
VS-H2A260-100	HSV-2 gC Monoclonal Antibody	100  μg
VS-H2A055-100	HSV-2 gE Monoclonal Antibody	100  μg
VS-H2A023-100	HSV-2 gG Monoclonal Antibody	100  μg
VS-H2A261-100	HSV-2 gH Monoclonal Antibody	100  μg
VS-H2A269-100	HSV-2 gH/gL Monoclonal Antibody	100  μg
VS-H2A262-100	HSV-2 gL Monoclonal Antibody	100  μg
VS-H2A024-100	HSV-2 ICP8 Monoclonal Antibody	100  μg

 

2. Varicella-Zoster Virus (VZV)

Varicella-Zoster Virus (VZV) is a highly contagious human herpesvirus that can cause primary infection (varicella, commonly known as chickenpox) and reactivation of latent virus in the body (herpes zoster, commonly known as shingles).

Virusys’ VZV antibody library focuses on the glycoprotein family essential for viral replication. Glycoprotein E (gE) is the most abundant envelope glycoprotein of VZV, which dominates viral cell-to-cell spread and immune evasion; while glycoprotein B (gB), as a key fusion protein, plays an irreplaceable role in the initial steps of viral entry into host cells.

Targeting key molecules such as gE and gB, Virusys provides validated VZV antibodies with high specificity. These antibodies can not only accurately localize the site of latent viral infection through techniques like immunofluorescence but also have become powerful visualization tools for uncovering the "latency-reactivation" switching mechanism of the virus and advancing related diagnostics and research.

 

Item Number	English Name	Specification
VS-VA032-100	VZV gB Monoclonal Antibody	100  μg
VS-VA315-100	VZV gE Monoclonal Antibody	100  μg
VS-VA034-100	VZV gI Monoclonal Antibody	100  μg
VS-VA036-100	VZV IE62 Monoclonal Antibody	100  μg

 

3. Cytomegalovirus (CMV)

Cytomegalovirus (CMV) is a herpesvirus that is highly prevalent in the human population but typically asymptomatic. However, it can cause severe diseases in immunocompromised individuals and newborns with congenital infections.

Virusys’ CMV antibodies target different stages of the viral life cycle (e.g., latency, immediate-early, late stages). The late antigen pp65 (UL83) is a key marker of active viral replication, and its expression in the late stage of infection serves as a core observation window for clinical diagnosis and research.

Targeting this critical molecule, Virusys provides high-quality CMV antibodies, represented by the CH12 antibody. As the "gold standard" for clinical antigenemia testing, this antibody can accurately localize viral assembly sites. Thanks to its unique unconjugated design, Virusys’ antibody has been widely cited in numerous top-tier scientific journals worldwide. Whether for research on congenital CMV infections or exploration of CMV replication mechanisms, it is a reliable tool you can trust.

 

Item Number	English Name	Specification
VS-CA005-100	CMV gB Monoclonal Antibody	100  μg
VS-P1212	CMV gB Monoclonal Antibody (CH177)	500  μg
VS-P1216	CMV gB Monoclonal Antibody (CH253)	500  μg
VS-P1201	CMV gB Monoclonal Antibody (CH28) - Non-neutralizing	500  μg
VS-CA010-100	CMV ICP22 Monoclonal Antibody	100  μg
VS-P1210	CMV ICP22 Monoclonal Antibody (CH41)	500  μg
VS-CA006-100	CMV ICP36 Monoclonal Antibody	100  μg
VS-P1202-1	CMV ICP36 Monoclonal Antibody (CH13)	500  μg
VS-P1202-2	CMV ICP36 Monoclonal Antibody (CH16)	500  μg
VS-P1209	CMV ICP8 (UL57) Monoclonal Antibody (CH167)	500  μg
VS-P1203	CMV IE1 Monoclonal Antibody (CH443)	500  μg
VS-P1215	CMV IE1/2  Monoclonal Antibody (CH160)	500  μg
VS-CA004-100	CMV pp28 Monoclonal Antibody	100  μg
VS-P1207	CMV pp28 Monoclonal Antibody (CH19)	500  μg
VS-CA003-100	CMV pp65 Monoclonal Antibody	100  μg
VS-P1205	CMV UL83 Monoclonal Antibody (CH12)	500  μg
VS-CA144-500	CMV UL84 Monoclonal Antibody	500  μg

 

4. Epstein-Barr Virus (EBV)

Epstein-Barr Virus (EBV) is a human herpesvirus with extremely widespread infection. It is not only a common cause of infectious mononucleosis but also closely associated with various malignant tumors such as multiple types of lymphoma and nasopharyngeal carcinoma.

During the pathogenic process of EBV, the immediate-early protein Ea-D serves as the "master switch" of the viral lytic cycle and is key to uncovering viral reactivation and exploring pathogenic mechanisms.

With high specificity, Virusys-brand EBV antibodies can accurately recognize Ea-D, making them reliable tools for your research on EBV infection diagnosis, viral reactivation mechanisms, and oncogenic mechanisms.

 

Item Number	English Name	Specification
VS-EA069-100	EBV Ea-D Monoclonal Antibody	100  μg
VS-EA068-100	EBV gp110 Monoclonal Antibody	100  μg

 

5. Virusys Polyclonal Antibody IgY

Virusys polyclonal antibody IgY is produced by immunizing animals with specific antigens, followed by serum collection, purification via Protein G, and purity verification using SDS-PAGE—its purity reaches over 90%. This antibody exhibits high sensitivity and broad reactivity, making it suitable for enzyme-linked immunosorbent assay (ELISA), Western blot, immunohistochemistry (IHC), and other immunological assays.

Virusys polyclonal antibodies undergo strict production quality control, which ensures batch-to-batch consistency and high specificity, effectively preventing cross-reactivity.

 

Item Number	English Name	Specification
VS-CA150-1	CMV Chicken IgY Ab - 1ml	1  ml
VS-EA223-1	EBV Chicken IgY Antibody – 1 ml	1  ml
VS-VA224-1	Varicella Zoster Chicken IgY Ab – 1 ml	1  ml
VS-VA225-1	VZV Glycoproteins Chicken IgY Ab – 1 ml	1  ml
VS-GA230-1	Normal Chicken IgY 1 mL	1  ml

 

Why Choose Virusys Viral Antibodies?

 

Comprehensive Target Coverage

Our antibodies cover key targets across the full spectrum of human herpesviruses, including common types such as HSV-1/2 and VZV, as well as tumor-associated viruses like EBV and CMV. They enable accurate recognition of various viral antigens, including matrix proteins, DNA-binding proteins, and membrane proteins.

 

Flexible Experimental Design

All antibodies are provided in an unconjugated format, allowing researchers to freely pair labels and detection systems according to experimental needs. They seamlessly adapt to multiple technical platforms, such as immunofluorescence (IF), Western blot (WB), and enzyme-linked immunosorbent assay (ELISA).

 

Excellent Quality Assurance

Leveraging hybridoma technology and serum purification techniques, combined with strict purification processes, we ensure all antibodies possess high specificity, high affinity, and high purity. Each antibody is validated to be free of active viral residues.

 

Brand Quality Certification

As a member of the LGC Group, our production complies with the ISO 13485 international quality management system. Product quality undergoes rigorous quality control, and our antibodies have been widely cited and recognized in numerous academic publications.

 

 

 

Virusys Corporation

Virusys Corporation is a biotechnology company dedicated to virology-related products and services. Founded in 1999 and headquartered in Taneytown, Maryland, USA, it specializes in virology-related products and services, and is renowned for its high-quality biological research reagents, professional monoclonal antibody technology, a wide range of viral detection products, and flexible custom services.

The company’s products are widely used in fields such as vaccine development, diagnostic reagent development, drug screening, and basic research, providing important tools for the prevention and control of infectious diseases and biomedical research. All Virusys antibody products undergo strict quality control and comply with the ISO 13485 quality management system standards to ensure batch-to-batch consistency and high specificity.

In October 2023, Virusys Corporation was acquired by the LGC Group and became part of LGC’s Clinical Diagnostics business. This acquisition has strengthened LGC’s product portfolio in the field of infectious diseases and further enhanced Virusys’ market position and influence in the virology sector.

 

As the China-based agent for the Seracare (Virusys) brand, Beijing XMJ Biotechnology Co., Ltd. is committed to promoting Virusys viral antibody products in China and providing high-quality products and professional services to a large number of domestic researchers. If you are interested in the products, please feel free to send email to info@xmjsci.com or visit the official website: www.mb020.com.cn for more information.